Human Genetic Potential and Chiropractic
HUMAN GENETIC POTENTIAL AND CHIROPRACTIC
The 21st century promises to be packed with exciting technical research and innovations and none is more promising than the rapidly growing field of human genetics. The next one hundred years can truly be called the century of human genetic potential.
FOR DNA: A DEFINING MOMENT
For a decade, the double stranded thread of genetic code known as the human genome project has been the object of the biggest and boldest biological enterprise ever launched, costing about two billion dollars and requiring millions of times the computing power used to land a man on the moon. The Human Genome Project, formally begin in 1990 with the goals of identifying the estimated 100,000 genes found in DNA, determining the sequence of the three billion chemical base pairs in DNA and storing information.
FUNDAMENTALS OF GENETICS
Genes:
Each gene is a double—stranded DNA that holds the recipes for making a specific molecule—usually a protein. These recipes are spelled out in varying sequences of four chemical bases in DNA. A (Adenine), T (Thymine), G (Guanine) and C (Cytosine). The base pairs form interlocking pairs that can fit together in only one way. “A” pairs with “T” and “C” pairs with: G”.
Proteins:
Proteins (Greek for “primary element”) are made up of polypeptide chains that in turn make amino acids, which are the body’s essential components of all organs and chemical activities. Some proteins, called enzymes, control the chemical reactions that occur within living things. The structure of a gene—that is the instructions contained in its DNA—determine which protein it makes and when it makes it
RNA: Ribonucleic acid is a single-stranded molecule located outside the nucleus that can be considered a ‘chemical slave” of DNA. RNA carries out the orders for a protein synthesis issued by DNA. There are three forms of RNA that work together to carry out the instructions of the DNA. They are:
Acquired (orsomatic) mutations occur in the DNA of individual cells at some time during a person’s life. These changes can be caused by environmental factors such as ultraviolet radiation from the sun, or can occur if a mistake is made as DNA copies itself during cell division. Acquired mutations in somaticcells (cells other than sperm and eggc ells) cannot be passed on to the next generation.
“X-rays, viruses, toxic chemicals and drugs can increase the likelihood of a change to the DNA, causing mutation that may lead to cancer and other disorders of the body.”
HUMAN GENETICS
Genetic research will lead to enormous potential in the fields of genetic testing and gene replacement therapy. However, the advent of this new technology should not be construed to mean that genetics represent the only factor affecting health. Indeed, emphasis and education on lifestyle, as well as environmental and structural factors will play a tremendous role in 21st century health care.
The environment in which you grow up is as importantasyour DNA in determining the person you ultimately become. You cannot disassociate genes from the environment that turns geneson and off; and you cannot disassociate the effects of genes from the environment in which proteins exert their effects. Certain genes lead to vulnerability, but not inevitability.
NEWSWEEK
For example, when geneticists say they've found a gene for a particular trait, what they mean is that people carrying a certain "allele"-- a variation in a stretch of DNA that normally codes for a certain protein will develop the given trait in a standard environment. The last few words--" in a standard --"environment" --are very important, because what scientists are not saying is that a given allele will necessarily lead to that trait in every environment. Indeed, there is mounting evidence that a particular allele will not produce the same result if the environment changes significantly; that is to say, the environment has a strong influence on whether and how a gene gets"expressed."
THE GENE IS NOT NECESSARILY DOMINANT
Genes are unquestionably the fundamental units by which our bodies are constructed. However, pure genetic determination does not adequately explain the varied capabilities of our biology. A more accurate view of the role of the genome is to see the genes as providing the overall plan for the developmental pathways. The environment to which the individual is exposed will modify the actual pathway”
PETER NATHANIELS, M.D.
“The major function of your genes is to transmit health and the inborn resolve to remember wellness. In the sickness paradigm, we are taught that disease-carrying genes determine our destiny. This is a false view. If we were truly destined to live by our genes, we would suffer from the thousands of diseases experienced by our ancestors for as long as we lived, which would not be very long at all. Disease-carrying genes are not our destiny, because they must answer to our inner compass-our healing force.”
EDWARD A. TAUB, M.D."
America's Wellness Doctor"
Research has revealed that there is no simple link between genes and health conditions. Genetics have something---but not everything—to do with health conditions. Genetics do not necessarily equal fate.
A NEW MODEL OF HEALTH CARE
Research projects around the world are showing great promise for the future of health care, and although these projects have barely scratched the surface, genetics research continues to rapidly change the way we view health care—from a disease and symptom model to one of performance and maximizing the inherent healing potential of the human body.
GREATER EXPECTATIONS:The future of health care lies not in treating illness,but preventing it
To maintain a high level of fitness, we must avoid physical decline—not repair it. Open heart surgery, even at its most effective, will never make the heart as good as new. The most effective preventive measures involve change in lifestyle. In addition, as genetic profiles and other predictive tools improve, the art of prevention will grow more sophisticated. Pressed by patients and advancing technology, health care will soon change its focus from treatment to enhancement, from repair to improvement, from diminished sickness to increased performance.The transformation has already begun. Accompanying this will be an increased emphasis on psychoimmunology, the science that deals with the mind's role in helping the immune system to fight disease, which will become a vitally important clinical field — perhaps the most importantfield in the 21st century.7
Michael Crichton, M.D.
“Health Care is going to change from treatment-based to prevention-based discipline.”
William Haseltine, Chairman Human Genome Science
“There is an alarming high number of disabling conditions-chronic diseases, most cancers, syndromes and other instances of poor health where western medicine is helpless. Thereis no root cause, no definite problem that surgery can eradicate or drugs can cure. A large part of the problem has to do with the theoretical frame work that modern medicine has taken on, namely that of ignoring the workings of the body itself”
Dr.I.William Lane, “Immune Power”
THE BODY’S HEALING SYSTEM
Genetic research, coupled with recent immunology research has clearly demonstrated the effectiveness and efficiency of the body’s healing system.
“The fact that healing is a natural power is a concept that is missing from traditional medicine.This seems to be the greatest defect of modern medicine—a defect that has immense practical significance since it underlies our ability to find cost effective solutions to common health problems.”
Andrew Weil, M.D.
“An automatic self-healing ability is programmed into our body’s genetic blueprint. The wisdom and “know-how” behind the body’s functioning is extremely complex. The body’s innate wisdom is more powerful than all of the accumulated knowledge of the human race. As we respect this by properly meeting the “essentials of health” we can utilize the “self-healing”blueprint that already exists within us.”
Arthur Baker
THE WONDER MACHINE
When cells are damaged, either externally through physical trauma or internally by toxins or parasites, the damaged cells release hundreds of chemical messengers that communicate the occurrence of damage to the central nervous system. The CNS responds by sending nerve messages that begin, coordinate and facilitate the entire healing process. The cardinal signs of inflammation—such as heat, fever, redness and pain are all signs that the healing process is proceeding on schedule.
CENTRAL NERVOUS SYSTEM & HEALING
“The nervous system is the most complex system in the body and it is estimated that as many as half of all genes are expressed in the nervous system. The intricate sequence of events leading from the earliest origins of the neural tube to the adult brain, spinal cord and peripheral nervous system is a complex process of gene expression and regulation.”
DEVELOPMENTAL BIOLOGY
The proper development and function of the nervous system is a primary key to maximizing the human genetic potential of health, healing and performance.
Molecular Genetics in Developmental Neurobiology
Molecular genetics in neurobiology has developed rapidly with the introduction of the new and productive methodologies of genetic engineering and cellular manipulation. Particularly in the field of developmental neurobiology, molecular genetics has had impact in research on the molecular mechanism if development and differentiation in the nervous system.
SYMPOISA OF BRAIN SCIENCES
Research has shown that activity that occurs at the molecular levels is controlled and coordinated by the central nervous system.
“The nervous system does much more than transmit sensory information to the brain or control motor functions. It actually controls the peripheral organs, including its biomolecular environment. The Central Nervous System is involved in all disease conditions as the CNS not only processes incoming physical and chemical information from the body, it actually controls organs and cells to maintain health and homeostasis.”
MEDICAL HYPOTHESIS
“We can only conclude that an analog-transmission and control system exists in the body, located in the perineural cells and transmitting information by means of the follow of semi-conducting DC electrical current. This system senses injury and controls repair, and it may serve as the morphogenic field itself. It controls the activity of body cells by producing specific DC electrical environments in their vicinity.”
ROBERT BECKER, M.D.
There is a greater quantity of biological communication in the human body than all of the man-made communication systems in the world combined. Signaling is essential to genetic expression
"No one could survive without precise signaling in cells. The body functions properly only because the cells constantly communicate with each other"
SCIENTIFIC AMERICAN
“All body systems would be immobilized with the nervous system. It controls and regulates every body activity down the workings of the tiniest cell.”
WORLD BOOK ENCYCLOPEDIA OF SCIENCE
Hormones do not damage or alter genes; rather they cause the gene to act in a certain way telling it when to activate or reproduce. It is much like a transmitter sending signals to a cell phone or a radio. If the nervous system is working properly, then the correct chemical message is sent to and received by the genes.
To exert their powerful influence in the body, hormones must first bind with specifically tailored cell proteins called receptors. There are hundreds of different kinds of receptors, each one designed for a specific chemical signal. Within one cell, there are 10,000 or more of one type of receptor, although a small number need to be activated to elicit a response. The receptor and its hormones have an intricate and precise fit, much like a lock and a key, and this hormone receptor then binds to the specific regions of the DNA in the cell nucleus to activate specific genetic sequences.
It would stand to reason that a breakdown in the control and coordination of the nervous system would result in decreased genetic expression.
“Individuals with the neurofibromatosis type 1 (NF1) inherited cancer syndrome exhibit neuronal dysfunction that predominantly affects the CNS resulting in vulnerability to reduced genetic expression.”
JOURNAL OF NEUROSCIENCE
VERTEBRAL SUBLUXATIONS
“Subluxations of vertebra occur in all parts of the spine and in all degrees. When the dislocation is so slight as to not affect the spinal cord, it will still produce disturbances in the spinal nerves passing off from the foramina.”
Dr. James Woddersee, Neurosurgeon
CHIROPRACTIC AND GENETIC POTENTIAL
In 1975, Ronald Pero, Ph.D., chief of cancer prevention research at New York’s Preventive Medical Institute and Professor of Medicine in Environmental Health at New York University, began developing scientifically valid ways to estimate individual susceptibility to various chronic diseases. Pero and his colleagues found strong evidence that susceptibility to cancer could be gauged by the activities of various enzymes involved in metabolic and genetic changes from exposure to carcinogenic or “mutagenic” chemicals. An individual’s immune system responsiveness, or “immune competence,” also was directly linked to certain DNA repairing enzymes that provided an objective way to assess disease susceptibility. Lack of those enzymes, Pero said, “definitely limits not only your lifespan, but also your ability to resist serious disease consequences.”
This connection led Pero to consider chiropractic a potential alternative for reducing the risk of immune breakdown and disease. Measuring 107 individuals who had received long term chiropractic care, Pero’s team had surprising findings. All chiropractic patients were `genetically normal,” that is, they had no obvious genetic reasons for increased resistance or susceptibility to disease. Any difference, therefore, had to be accounted for by environmental or therapeutic factors.